Ailments : A-Z

IR™ (Diabetes)
Rowland Formula 18

IR™ is a unique formulation that reduces insulin resistance, enabling cells to make more efficient use of glucose. It is of particular benefit to type II diabetes (non-insulin-dependent) –and also provides some benefit to type I diabetes.

Suggested Use: 4 capsules daily, in divided amounts with meals.

Synergistic Support for IR™

Insulex™ a homeopathic dilution that stimulates the body to overcome any resistance (allergy) it may have to the beta pancreatic cells or to insulin itself. Of primary benefit to type I diabetes and may also be of benefit to many cases of type II.

RTRE™ Every diabetic is at elevated risk for cardiovascular disease. RTRE is vitally necessary to protect the arteries and to prevent the retinopathy and gangrene that are normally associated with diabetes.

The following details indicate how the ingredients in IR™ work together synergistically to reduce insulin resistance:

Chromium
Glucose intolerance is a symptom of chromium deficiency1 — in which case glucose uptake in insulin-sensitive tissues is impaired.2 Serum chromium levels are correlated with serum insulin levels.3 Chromium supplementation improves glycemic response in non-insulin-dependent4 and gestational diabetics.5

Magnesium
Magnesium intake is inversely related to the risk of diabetes6 as well as fasting serum insulin levels.2 Only 20% of non-insulin-dependent diabetics meet the RDA for magnesium.8

Magnesium nurtriture is depressed in diabetics.9 Hypomagnesia may result from increased urinary magnesium excretion as a result of glycosuria.16 Reduced erythrocyte and platelet magnesium concentrations are also common."

Magnesium activates the key enzymes of glycolysisI2, and magnesium supplementation may improve glycoregulation by improving insulin response. t3

Vanadium
Vanadium salts mimic most of the effects of insulin on the main target tissues of the hormone. They may induce a sustained fall in blood glucose levels in insulin-deficient diabetics, and improve glucose homeostasis in obese, insulin-resistant diabetics.'4

For non-insulin-dependent diabetics, vanadium salts show reduction of insulin resistance.I4 Supplementation reduces fasting glucose and glycosylated haemoglobin concentrations.I6 Vanadium may act by preventing hyperinsulinemia, partly because of its own insulin activity!'

Zinc
Zinc nutriture is important to glycoregulation. Those on a low-zinc diet may develop a significant increase in fasting blood glucose.18 Only 14% of non-insulin-dependent diabetics meet the RDA for zinc.8 Low groundwater levels of zinc are directly related to the risk of insulin-dependent diabetes.°

Zinc metabolism in diabetes appears to be abnormal. Non-insulin-dependent diabetics may show evidence of zinc malabsorption.2° Hyperzincuria is common in both insulin-dependent2I and non-insulindependent22 diabetics and may correlate with serum glucose levels23 and the degree of glycosuria24. Tissue and blood22 zinc levels are frequently depressed. Normal volunteers who received zinc supplements showed increased glucose assimilation and efficiency.26

Alpha-Lipoic Acid
In diabetes, cellular sugar uptake is impaired; and alpha-lipoic acid (thioctic acid) stimulates glucose carriers to increase sugar uptake in cells, thus improving insulin action. Supplementation with alpha-lipoic acid has been found to increase insulin action27, improve energy metabolism,I5 It also reduces the symptoms of diabetic peripheral neuropathy and the heart rate variability of diabetic autonomic neuropathy, in non-insulin-dependent diabetics.28

Gymnema Sylvestre
Gymnema sylvestre is a woody climbing plant that grows in the tropical forests of central and southern India. Its leaves have been used as an adjunct in the trea™ent of diabetes mellitus for many centuries. Water-soluble extracts of these leaves have been shown to reduce blood glucose and increase endogenous insulin levels in type II diabetics29 and to reduce both blood glucose and insulin requirements in type I diabetics.3° Gymenema sylvestre may also increase the number of islets of Langerhans and the number of beta cells in the pancreas.31

Blueberry Leaf
Blueberry leaf (vaccinium corymbosum) is a traditional native North American remedy for diabetes.32 The active ingredient in the leaf that is attributed with this effect is myrtillin.

Glycine
Glycine is a non-essential amino acid that stimulates glucose oxidation. Supplements which provide the glycine molecule to the body include trimethylglycine (betaine), and magnesium glycinate.

1. Freund H et al. Chromium deficiency during total parenteral nutrition. JAMA 241(5):496-8, 1979.
2. Mertz W. Chromium occurrence and function in a biological system. Physiol Rev 49:163-230, 1969.
3. Liu V1, Abernathy RP. Chromium and insulin in young subjects with normal glucose tolerance. Am J Clin Nutr 25(4):661-7, 1982.
4. Anderson RA et al. Elevated intakes of supplemental chromium improve glucose and insulin variables in individuals with Type 2 diabetes. Diabetes 46(11):1786-91, 1997.
5. Jovanovic-Peterson L et al. Chromium supplementation for gestational diabetic women improves glucose tolearance and decreases hyperinsulinemia. J Am Coll Nutr 14(5):530, 1995.
6. Colditz GA et al. Diet and risk of clinical diabetes in women. Am J Clin Nutr 55:1018-23, 1992.
7. Ma J et al. Associations of serum and dietary magnesium with cardiovascular disease, hypertension, diabetes, insulin and carotid artery wall thickness. J Clin Epidemiol 48(7):927-40, 1995.
8. Schmidt Let al. Evaluation of nutrient intake in subjects with NIDDM. J Am Diet Assoc 94(7):773-4, 1994.
9. Durlach J, Collery P. Magnesium and potassium in diabetes and carbohydrate metabolism. Magnesium 3(4-6):315-23, 1984.
10. Tosiello L. Hypomagnesia and diabetes mellitus. Arch Int Med 156:1143-8, 1996.
11. Corica F et al. Magnesium levels in plasma, erythrocyte, and platelets in hypertensive and normotensive patients with NIDDM. Biol Trace Elem Res 51:130-2, 1996.
12. Elamin A, Tuvemo T. Magnesium and IDDM. Diabetes Res Clin Pract 10:203-9, 1990.
13. Paolisso G et al. Improved insulin response and action by chronic magnesium administration in aged NIDDM subjects. Diabetes Care12:265-69, 1989.
14. Brichard SM, Henquin JC. The role of vanadium in the management of diabetes. Trends Pharmacol Sci 16(8):265-70, 1995.
15. Barbiroli B. Thioctic acid - a rational remedy for the trea™ent of diabetic polyneuropathy. Exp Clin Endocrinol Diabetes 104:126-7, 1995.
16. Halberstam M. Oral vanadyl sulphate improves insulin sensitivity in NIDDM. Diabetes 45:659-66, 1996.
17. Sprietsma JE, Shuitemaker GE. Diabetes can be prevented by reducing insulin production. Med Hvootheses 42(1):15-23, 1994.
18. Solomon SJ, King JC. Effect of low zinc intake on carbohydrate and fat metabolism in men. Fed Proc 42:391, 1983.
19. Haglund B et al. Evidence of a relationship between childhood-onset type I diabetes and low groundwater concentration of zinc. Diabetes Care 19(8):873-5, 1996.
20. Kinlaw WB et al. Abnormal zinc metabolism in type II diabetes mellitus. Am J Med 75(2):273-7, 1983.
21. Cunningham JJ et al. Hyperzincuria in individuals with IDDM. Metabolism 43:1558-62, 1994.
22. Chen M-D et al. Selected metals status in patients with NIDDM. Biol Trace Elem Res 50:119-24, 1995.
23. Kinlaw WB et al. Abnormal zinc metabolism in type II diabetes mellitus. Am J Med 75(2):273-7, 1983.
24. McNair P et al. Hyperzincuria in insulin treated diabetes mellitus. Clin Chim Acta 112:343-8, 1981.
25. Sjogren et al. Magnesium, potassium and zinc deficiency in subjects with type II diabetes mellitus. Acta Med Scand 224:4613, 1988.
26. Brun J-F et al. Effects of oral zinc gluconate on glucose effectiveness and insulin sensitivity in humans. Biol Trace Elem Res 47:385-91, 1995.
27. Jacob S et al. Improvement of insulin-stimulated glucose-disposal in type 2 diabetes after repeated parenteral administration of thioctic acid. Exp Clin Endocrinol Diabetes 104(3):284-8, 1996.
28. Ziegler D. Gries FA. Alpha-lipoic acid in the trea™ent of diabetic peripheral and cardiac autonomic neuropathy. Diabetes 46(Suppl. 2):S62-S66, 1997.
29. Baskaran K et al. Antidiabetic effect of a leaf extract from Gymnema sylvestre NIDDM patients. J Ethnopharmacol 30:295- 305, 1990.
30. Shanmugasundaram ERB et al. Use of Gymnema sylvestre leaf extract in the control of blood glucose in IDDM. J Ethnophannacol 30:281-94, 1990.
31. Shanmugasundaram ERB et al. Possible regeneration of the islets of Langerhans in streptozotoc n-diabetic rats given Gymnema sylvestre leaf extracts. J Ethnopharmacol 30:265-79, 1990.
32. Blumenthal et al. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines, American Botanical Council, 1998.

IR™ Statement of Fact

By sharing her true experiences with you, this person is exercising the "freedom of thought, belief and expression" guaranteed by Canada's Charter of Rights and Freedoms (Constitution Act, 1982).

Diabetes Success
"After taking IR™ for just a couple of weeks, my 79-year old husband with type II diabetes has been able to cut his medication in half. He measures his glucose level every morning and it has remained steady. His doctor is amazed at how well he is doing.

"I am aged 77 and have been taking PAYN-EZ for a number of years. I am thrilled to say that I am the only member of my large family that doesn't suffer from any type of arthritis or body pain."
- Grace Stringer, Bancroft, ON

Payn-Ez™ (Arthritic & Body Pain)
Rowland Formula 21

Pain is the body's way of letting us know that some of our tissues are in trouble. Drugs only mask the pain. By numbing our senses, they allow us to continue doing whatever it is that is causing the problem. Nature has a better way. Osteoarthritis, rheumatoid arthritis, fibromyalgia, bursitis, tendonitis and sports injuries can all be nourished into recovery using Payn-Ez™. Its unique blend of ingredients help to reduce inflammation, rebuild cartilage and connective tissue, and regenerate the synovial fluid that lubricates joints. As damaged tissues are rebuilt, the pain diminishes accordingly. PAYN-EZ is also effective instead of prescription pain relievers to reduce and eliminate pain during post-surgical recovery.

Ingredients: marine lipid concentrate (EPA & DHA), glucosamine sulphate, N-acetyl-dglucosamine, chondroitin sulphate, proanthocyanidins, shark cartilage, gamma-linolenic acid, bilberry extract, manganese aspartate, ascorbyl palmitate (fat soluble vitamin C), and d-alpha tocopherol (vitamin E).

Suggested Use: Take as many capsules as necessary to provide immediate relief from the pain, to a maximum of 12 per day. Over the next two weeks, gradually reduce this amount to 4 capsules per day – or to whichever maintenance level provides consistent freedom from pain. Higher amounts are needed initially to saturate tissues. Once saturation has been reached, less PAYN-EZ is required. Those with acute injuries may be able to wean themselves off PAYN-EZ within days or weeks. Those with chronic arthritic pain may eventually be able to eliminate the need for PAYN-EZ if they correct the cause of their arthritis (often hidden food allergies) and support their bodies with broad spectrum formulas such as PLUS™ or RTRE™.

Marine Lipids
Fish body oils provide eicosapentaenoic acid (EPA) and docosahexanoic acid (DHA). Fish oil supplements are often used to treat rheumatoid arthritis — with resulting reduction in tenderness, joint swelling and morning stiffness — plus improved grip strength. EPA is required for the production of the prostaglandins that reduce inflammation and limit the production of the pro-inflammatory leukotrienes.

Glucosamine
Glucosamine, derived from glucose, is used as a building block for the synthesis of glycoproteins, glycosamines, mucopolysaccharides, and proteoglycans. (Glycosamines are key structural components of cartilage.) Glucosamine inhibits cartilage breakdown and reduces inflammation. It stimulates the body's manufacture of chondroitin sulphate, another substance needed for proper joint function and joint repair.

Therapeutically, glucosamine is used to repair cartilage that has been damaged from accident or sports injuries and cartilage that has been eroded by osteoarthritis. Glucosamine has been shown to reduce joint pain, tenderness and swelling, and to improve range of motion and walking speed. Numerous double blind studies have shown glucosamine sulphate to be more effective than non-steroidal anti-inflammatory drugs (NSAIDs) in relieving the pain of osteoarthritis. Glucosamine works more slowly than NSAIDs but produces longer lasting relief.

There are no food sources for glucosamine; it is produced endogenously. As we age, our bodies tend to produce less glucosamine, with the result that cartilage loses its ability to absorb shocks. As a supplement, it is available in two forms: glucosamine sulphate and N-acetyl-D-glucosamine.

Chondroitin Sulphate
Therapeutically, glucosamine is often combine with chondroitin sulphate, a substance that also reduces inflammation and protects cartilage against breakdown. Glucosamine and chondroitin supplementation (both together and separately) have been shown to decrease significantly the severity of osteoarthritis.

Chondroitin sulphate is a mucopolysaccharide that the body uses to make proteoglycans, substances that function in cartilage to maintain elasticity, strength and mass.

Shark Cartilage
Shark cartilage contains a mixture of glycosaminoglycans, including chondroitin sulphate. Shark cartilage is often used to treat osteoarthritis. It also has the ability to inhibit tumour growth and may be of benefit to such conditions as diabetic retinopathy, macular degeneration, psoriasis, and bowel inflammation.

Red Wine Proanthocyanidins
Proanthocyanidins are flavonoids that act as antioxidants. They are used therapeutically to reduce the inflammation of arthritis and tendonitis. They do so by countering the substances that mediate inflammation (e.g., histamines, prostaglandins, leukotrienes, serine proteases). Proanthocyanidins also strengthen collagen and elastin structures, scavenge free radicals, and reduce the effects of aging. Users report smoothing of wrinkles, softening of lines, lightening of aging spots, and improved flexibility of joints. The anti-inflammatory and collagen rebuilding properties of proanthocyanidins make them an ideal trea™ent for athletic injuries. Collagen forms the matrix for all connective tissue (cartilage, tendons, ligaments). Proanthocyanidins strengthen collagen by reinforcing its natural cross-linking structure and by inhibiting its destruction from enzymes secreted by leukocytes during inflammation.

Bilberry
Bilberry (European blueberry, huckleberry) is a rich source of flavonoids, including anthocyanidins, proanthocyanidins, and quercetin. These substances enhance collagen matrix integrity and structure. They also have antioxidant and anti-inflammatory actions that are beneficial to the trea™ent of rheumatoid arthritis. Bilberry also helps to relax smooth muscles.

Borage Oil
Borage seed oil is a rich source of gamma-linolenic acid (GLA), a building block for the formation of prostaglandins, hormonelike substances that help to regulate the immune, nervous and cardiovascular systems. GLA has been shown to reduce the joint swelling and tenderness associated with rheumatoid arthritis.

Manganese
Manganese supplements are often used to treat inflammation, strains and sprains. Manganese helps to raise the body's level of superoxide dismutase (SOD), an enzyme that protects against the oxidative damage that accompanies rheumatoid arthritis and other chronic inflammatory conditions. Without sufficient SOD, cells are susceptible to damage and inflammation caused by free radicals.

References:
Groff, JL, Gropper, SS. Advanced Nutrition and Human Metabolism. Belmont, CA: Wadsworth, 2000.
Heimlich, H, What Your Doctor Won't Tell You. New York: HarperCollins, 1990.
Murray, MT. Encyclopedia of Natural Medicine. Rocklin, CA: Prima Publishing, 1991. Murray, MT. Encyclopedia of Nutritional Supplements. Rocklin, CA: Prima Publishing, 1996. Reavley, N. New
Encyclopedia of Vitamins, Minerals, Supplements & Herbs. New York: Evans, 1998. Rowland, DW.
Nature's Medicines. Parry Sound, ON: Rowland Publications, 1991.
Werbach, MR. Nutritional Influences on Illness (2nd ed.). Tarzana, CA: Third Line, 1993.

Pavn-Ez ™ Statements of Fact

By sharing their experiences with you. these people are exercising the "freedom of thought, belief and expression" guaranteed by Canada's Charter of Rights and Freedoms (Constitution Act, 1982).

Pain Free Recovery
"In 1989 I was diagnosed with progressive osteoarthritis. If the doctors had their way, I would have had one new hip joint immediately and possibly the second a year later. Thanks to the creative mind of David Rowland and CNC products, I have not had even as much as a common cold in the last 10 years.

"About 12 months ago, I noticed that I couldn't travel long distances in my car anymore. The pain in my left hip became so unbearable that 15 minutes of driving was about all I could stand. Even at my computer, or my desk, 15 minutes sitting anywhere was all I could tolerate. Having done all I could for the last 10 years, it was finally time to have the hip joint replaced.

"As a sceptic, I must admit that the operation went extremely well. When I came out of the anaesthesia, I drank only liquids for 24 hours, until I felt well enough to eat.

"When I started eating, that's when I started loading up my meals with hosts of supplements. One in particular, which CNC had just introduced, was Payn-Ez™. The amazing thing about this was when the nurse came around to give us our painkillers, every other man in my room was anxiously awaiting his pill. When she came to my bed and I said that I didn't need one, all eyebrows went up. I just smiled. Not wanting to cause any fuss, I said that I was doing just fine on my supplements.

"The amazing truth is that I never took one doctor-prescribed painkiller at all after my operation. Anyone who has had major surgery can well appreciate what that means. To date – three months to be exact – I still have not taken any painkillers. I have had tremendous results with this new product, PAYNEZ™.

"I took three weeks off to convalesce at my brother's place in Florida. That meant two days driving down and two days driving back. My supplements, including PAYN-EZ™, were the only medicine I needed – absolutely no pain whatever.

"If ever David Rowland has created a winner (other than the arterial cleansing formula) it's this new formulation, PAYN-EZ™ ... You know, maybe there is something very special behind the name, Creative Nutrition Canada, that we haven't fully appreciated. Thanks, David. I really do owe you a lot."
- Tony Holder, Peterborough, ON

Pain-Free Pet
"My dog, Toby – a beagle – had a very painful back-end and was not able to jump up on my husband's chair as usual or could not make the stairs. After the administration of Payn-Ez™, the pain stopped and he was able to resume his normal activities – had no adverse effects and the relief came overnight.

"On Day 1 we gave Toby two Payn-Ez™ in the morning with food, and two in the evening with food. On Days 2 & 3 we gave him one at breakfast and one at supper. On Day 4 and for the rest of the week we gave him one per day.

"I hope that this may help some other pets that are having a hard time of it. After all, their life is not as long as ours and they should live pain-free."
- Debby Best, Apsely, ON

Proanthocyanidins (Inflammation)

Proanthocyanidins are potent bioflavonoids that help to increase intracellular levels of vitamin C, to decrease capillary fragility and permability, to strengthen collagen and elastin structures, to scavenge oxygen and free radicals, and to reduce the effects of aging. Proanthocyanidins are at least 20 times more potent than vitamin E in neutralizing the iron and oxygen species of free radicals that attack lipids.

Proanthocyanidins are also effective at reducing inflammation of various tissues in the body. These are the conditions that typically end in the suffix "-itis" (e.g., bursitis, arthritis, tendonitis, phlebitis, thrombophlebitis). The anti-inflammatory and collagen-rebuilding properties of proanthocyanidins make them an ideal trea™ent for athletic injuries.

The powerful antioxidant and free-radical scavenging properties of proanthocyanidins counter free radical damage to collagen, connective tissue, RNA and DNA – thus enabling a person to feel and look younger. Users report smoothing of wrinkles, softening of lines, lightening of age spots, and improved flexibility of joints.

Suggested Use: (inflammation): 3 to 6 capsules daily, between meals. (general health): 1 to 3 capsules daily, with meals.

Ingredients: Each capsule contains 50 mg. of Proanthocyanidins from red wine grapes grown without pesticides or other agricultural chemicals. This water soluble powder is rich in anthocyanidins, leucocyanidins, flavones, and tannins. Produced 100% by a water process.

STH™ (Anti-Aging)
Rowland Formula 22

STH™ is a synergistic blend of amino acids and supporting factors that stimulate the body's production of human growth hormone (HGH) – also known as somatotropin. This is an ideal formula for those who wish to lower their biological age – to look and feel younger, have more energy, increased libido, improved sleep patterns, etc. Also ideal for athletes, bodybuilders and dieters who wish to increase muscle mass.

The anterior pituitary gland secretes somatotropin or "growth" hormone, although this term is not accurate since HGH is produced throughout life and is responsible for much more than growth. It acts directly on most bodily tissues to promote protein deposits necessary for growth, repair, healing and cellular maintenance. It builds muscle, burns fat and improves exercise performance. HGH also stimulates the liver to release fatty acids for energy when blood sugar levels drop during times of stress. A more appropriate name for HGH would be the "youth" hormone.

As the body ages, its production of somatropin declines – and this lack of HGH directly contributes to bodily deterioration. The rate of decline of HGH varies from person to person. STH™ stimulates the body to restore its production of HGH to a more youthful level.

Suggested Use: Take 5 capsules with the evening meal – provided that meal contains a substantial amount of protein. It if it does not, then take 5 capsules on an empty stomach, immediately before going to bed. [Note: Taking STH™ with carbohydrates significantly dilutes its effect.]

Ingredients: L-Arginine, L-Ornithine Alpha Ketoglutarate, L-Glutamine, L-Glycine, Hypothalamus, Adenosine Tri-Phospate, L-Pyroglutamic Acid.

Synergistic Support for STH™

CoQ10 functions as a metabolic activator that stimulates cells to make more efficient use of the amino acids in STH™.

Pro-Fibe™ protein supplement for athletes, bodybuilders and dieters.

PLUS™ high potency multi vitamin/mineral formula for athletes, bodybuilders and dieters.

L-Arginine
Arginine is a component of the pituitary hormone, vasopressin, and assists in the release of somatotropin ("growth" hormone). This amino acid is also a component of collagen and aids in building new bone and tendon cells. It is found in high concentrations in skin and connective tissue, where it aids the repair of damaged tissue. Arginine facilitates an increase in muscle mass and a reduction in body fat. It is also a constituent of semen and is often used to treat sterility in men

L-Ornithine
Ornithine prompts the release of somatotropin ("growth" hormone), which promotes the building of muscle and the breaking down of excess fat. High concentrations of ornithine are found in skin and connective tissue, where it promotes healing of damaged tissues. Ornithine is synthesized in the body from arginine, and the effects of both these amino acids are enhanced if taken together. L-ornithine alpha ketoglutarate is the most active form of ornithine.

L-Glutamine
Glutamine is the most abundant free amino acid in muscle tissue, where it is needed for the synthesis of skeletal muscle proteins. Glutamine also passes the blood-brain barrier to act as a brain fuel. In the brain, glutamine is converted into glutamic acid, the only amino acid metabolized by the brain. (Glutamic acid is an excitatory neurotransmitter that increases the firing of neurons in the central nervous system.) Glutamine also increases the amount of GABA (gamma amino butyric acid), which is needed to sustain proper brain function and mental activity. Glutamine promotes mental ability, provides the raw materials for synthesizing RNA and DNA, and helps to maintain a healthy digestive tract. Because glutamine helps to build and maintain muscle, it is a favourite supplement of dieters and bodybuilders. It also helps to prevent the muscle wasting that accompanies prolonged bed rest or trauma – because stress and injuries can cause muscles to release up to one-third of their glutamine into the bloodstream, thus losing much of their mass. Supplemental L-glutamine is used to enhance mental functioning, to relieve fatigue, and to treat such age-related conditions as impotence and senility.

L-Glycine
Glycine retards muscle deterioration by supplying creatine, a substance in muscle tissue that is also used for the construction of DNA and RNA. Because high concentrations of glycine are found in the skin and connective tissue, glycine helps to repair damaged tissues and promote healing. Glycine also boosts the body's production of phosphocreatine, a muscle energy fuel.

Hypothalamus
The hypothalamus is an area of the brain that controls the pituitary gland, which in turn regulates other endocrine glands. The hypothalamus contains cells that help control bodily temperature, fluid balance, sleep, appetite, and the emotions of fear and pleasure. The hypothalamus influences heartbeat and the contraction of and relaxation of blood vessel walls. Some of its cells control the production of heat in bodily tissues and others control heat loss from the body. Taking hypothalamus concentrate from animal tissues provides intrinsic cellular support to the human hypothalamus.

Adenosine Tri-Phospate
Adenosine Tri-Phosphate (ATP) is an energy acceptor found in every cell of the body. ATP can give up its energy to another compound of the cell at whatever place work is being done. ATP in this formula is an energy donor to enable the cells to make more efficient use of the other ingredients in the formula.

CHL™ (Cholesterol & Triglycerides)
Rowland Formula 23

CHL™ is an effective cholesterol-lowering formula – entirely natural and without side effects of any kind – and is more effective than prescription drugs. CHL is best used for those stubborn cases of hypercholesteremia that don't respond to RTRE™ and/or to thyroid therapy (TSF™ and Thyrex™). [Elevated cholesterol is an often overlooked symptom of hypothyroidism.] CHL also lowers serum triglyceride levels.

Suggested Use: 2 capsules daily, in divided amounts with meals.

Synergistic Support for CHL™

Niacin Another natural and safe cholesterol-lowering agent.

RTRE™ Clears arteries and provides cholesterol-reducing antioxidants.

TSF™/Thyrex™ Reduces elevated cholesterol caused by hypothyroidism.

Red Yeast Rice
Red yeast rice is rice that has been fermented by the red yeast, Monascus purpureus. It has been used in China for over 1,000 years for medicinal purposes, including improving the circulation and for alleviating indigestion and diarrhea. Recently, red yeast rice has been developed by Chineses and American scientists as a product that lowers blood lipids, including cholesterol and triglycerides. In 1977, Professor Endo in Japan discovered a natural cholesterol-lowering substance produced by M purpureus yeast. This substance inhibits the HMG-CoA reductase enzyme that is important for the production of cholesterol in the body. Professor Endo called this substance moncacolin K. Since then, scientists have discovered a total of eight like substances in red yeast rice that also have cholesterol-lowering properties. Together these eight substances and their natural co-factors found in red yeast rice lower total cholesterol, lower LDL cholesterol, lower triglycerides, and increase HDL cholesterol.

Guggul Resin
Guggul resin is a standardized extract of the mukul myrrh tree, native to India. Its active components are Z-guggulsterone and E-guggulsterone. Several clinical studies have confirmed that guggul resin has an ability to lower both cholesterol and triglycerides comparable to that of lipid-lowering prescription drugs.1'2 While those drugs are associated with toxicity, guggul is without side effects and is safe to use during pregnancy. Guggul lowers cholesterol by improving the liver's metabolism of LDL cholesterol.' Guggul also has a mild effect in inhibiting platelet aggregation and promoting fibrinolysis, implying that it may also prevent the development of a stroke or embolism.'

Pantethine
Pantethine is the stable form of pantetheine, which is the active form of pantothenic acid (vitamin B-5). Pantethine has significant effect in lowering cholesterol and tri-glyceride levels, while pantothenic acid has little or none. Pantethine has been shown to reduce significantly serum triglycerides (by 32%), reduce total cholesterol levels (by 19%), reduce LDL cholesterol levels (by 21%), and increase HDL cholesterol levels (by 23%).3'4 There appears to be no toxicity or side effects from taking pantethine. Several clinical studies have shown that pantethine produces impressive lipid-lowering effects without side effects in diabetics.5'6'7

Phytosterols
Phytosterols are cholesterol analogs found in vegetables. Their administration may decrease cholesterol absorption by displacing cholesterol from bile salt micelles.8 Phytosterols reduce plasma total and LDL cholesterol levels without affecting HDL cholesterol. 9 When taken with meals containing cholesterol, phytosterols may reduce cholesterol absorption by up to 42%.19 Phytosterols may also improve the reduction of LDL cholesterol achieved with lovastatin drugs by an additional 13 to 15%.11

1 . G.V. Satyavati, "Gugulipid: A Promising Hypolipidaemic Agent from Gum Guggul (Commiphora wightii)," Econ Med Plan Res 5 (1991):47-82.
2. S. Nitayanand, J.S. Srivastava, and O.P. Asthana, "Clinical Trials with Gugulipid, a New Hypolipidaemic Agent," J Assoc Phys India 37 (1989):321-8.
3. L. Arsenio, P. Bodria, G. Magnati, et al., "Effectiveness of Long-Term Trea™ent with Pantethine in Patients with Dyslipidemias," Clin Ther 8 (1986):537-45.
4. A. Gaddi, et al. "Controlled Evaluation of Pantethine, a Natural Hypolipidemic Compound, in Patients with Different Forms of Hyperlipoproteinemia," Atheroscl 50 (1984):73-83.
5. F. Coronel et al., "Trea™ent of Hyperlipidemia in Diabetic Patients on Dialysis with a Physiological Substance," Am J Nephrol 1l(1)(1991):32-6.
6. C. Donati, R.S. Bertieri, and G. Barbi, "Pantethine, Diabetes Mellitus, and Atherosclerosis: Clinical Study of 1045 Patients," Clin Ter 128(6) (1989):411-22.
7. K. Hiramatsu, H. Nozaki, and S. Arimori, "Influence of Pantethine on Platelet Volume, Microviscosity, Lipid Composition, and Functions in Diabetes Mellitus with Hyperlipidemia," Tokai J Exp Clin Med 6(1) (1981):49-57.
8. A. Ikeda et al, "Inhibition of Cholesterol Absorption in Rats by Plant Sterols," J Lipid Res 29(12) (1988):1573-82.
9. T.A. Miettinen et al, "Reduction of Serum Cholesterol with Sitostanol-ester Margarine in a Mildly Hypercholesterolemic Population," N Engl J Med 333(20) (1995): 1308 -12 .
10. F.H. Mattson et al, "Optimizing the Effect of Plant Sterols on Cholesterol Absorption in Man," Am J Clin Nutr 35(4) (1982):697-700.
11. W.O. Richter et al, "Trea™ent of Severe Hypercholesterolemia with a Combination of Beta-Sitosterol and Lovastatin," Curr Ther Res 57(7)(1996):497 -505.

CoQ10 (Antioxidant)

Coenzyme Q10 (also known as ubiquinone) is an essential component of the mitochondria – the energy producing unit of the cells of our body. CoQ10 is involved in the manufacture of adenosine tri-phosphate (ATP), which is the energy currency of all bodily processes. CoQ10 functions like a spark plug in a car engine – just as the car cannot function without the initial spark, neither can the body function without CoQ10

CoQ10 is in every plant and animal cell. There are tiny amounts in our diet, especially from plant foods. The human body also makes its own CoQ10, and its ability to do so declines with age. The beneficial effects of CoQ10 revolve around its ability to improve energy production and to act as an antioxidant. Therapeutically, CoQ10 has been demonstrated to be of benefit to such conditions as AIDS, atherosclerosis, cancer, cardiac arrhythmias, cardiomyopathy, chronic fatigue, congestive heart failure, diabetes mellitus, hypertension, immunodepression, inner ear dysfunction, mitral valve prolapse, muscular dystrophy, myopathy, neuralgia, neuropathy, obesity, periodontal disease and sports injuries.

The body can usually make all of the CoQ10 it needs from a high intake of vitamin C. Those who take RTRE™, CNR™, or DTX™ at the full daily recommendation rarely need to take extra CoQ10. The main exception is that anyone taking prescription drugs to lower cholesterol will need to take extra Coenzyme Q10 to compensate for the CoQ10 that these drugs destroy.

CoQ10 also acts as a catalyst to help the body make more efficient use of STH™, the rejuvenation formula. In this case, take the CoQ10 at the same time as the STH.

Suggested Use: 1 capsule daily, with food.

Ingredient: Coenzyme Q10. 60 mg. per capsule.

ELECTRA (Nerves)
Formulated by Richard DeSylva

ELECTRA is a nerve tonic and natural sedative that not only provides immediate relief from nervous tension but also gradually helps to restore the nerves – thanks to the generous amounts of easily assimilable salts of calcium, magnesium and silica it provides. The herbs in ELECTRA also provide specific compounds that soothe and sedate an overactive mind and body. Two of its ingredients, St. John's Wort and Scullcap, are of immense benefit to nerve exhaustion, sleep disruptions, volatility of the nerves, and even mild to moderate cases of depression. Valerian root helps to promote a deep and sound sleep, while Motherwort and Mistletoe calm the heart.

This formula can be used over long periods of time to act as a restorative for the nerves. Equally, it can be used for the short term, in cases of disrupted sleep due to moments of stress. In either case, it is safe, effective, and sure in its effect.

Suggested Use: For poor sleep: 3-4 capsules before retiring.
As a restorative: 2 capsules mid-morning, and again late afternoon, or mid-evening. (4 capsules total daily)
For best results take on an empty stomach.

Ingredients: Scullcap, Valerian root, Blue Vervain, St. John's Wort, Chamomile flowers, Mistletoe, Motherwort, Red Clover, Catnip.

Contraindications: Not to be used in combination with either MAO inhibitors or SSRI agents (e.g., Paxil).
Not to be used in combination with other herbal sedatives, unless recommended by a qualified practitioner.
Not to be used during pregnancy or lactation.
Not to be used by those on heart medications.